Family 9.B.1 - The Metal Homeostasis Protein (MHP) Family

Family ID: 53384
A single protein from Saccharomyces cerevisiae constitutes the
MHP family. This protein, Bsd2, is involved in metal homeostasis
and may transport Cu2+, Mn2+, Co2+ and Cd2+ in the endoplasmic
reticulum. Bsd2 may indirectly regulate protein trafficking between
the endoplasmic reticulum, the plasma membrane and the endosomes.
It may also mediate sensitivity to oxygen in intact yeast cells.
Bsd2 has 321
amino acyl residues with three putative transmembrane a-helical
spanners.