MATE Family


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Family 2.A.66 - The Multi Antimicrobial Extrusion Family

Family ID: 52642

The MATE family includes several sequenced members from bacteria and yeast. These proteins include a functionally characterized multidrug efflux system from Vibrio parahaemolyticus,NorM, and several homologues from other closely related bacteria that function by a drug:Na+antiport mechanism, a putative ethionine resistance protein of Saccharomyces cerevisiae,and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. The bacterial proteins are of about 450 amino acyl residues in length and exhibit 12 putative TMS. They arose by an internal gene duplication event from a primordial 6 TMS encoding genetic element. The yeast proteins are larger (up to about 700 residues) and exhibit about 12 TMSs.

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	Arabidopsis Families
	At1g11670 unknown protein At1g12950 unknown protein At1g15150 hypothetical protein At1g15160 hypothetical protein At1g15170 hypothetical protein At1g15180 hypothetical protein At1g23300 conserved hypothetical protein At1g33080 hypothetical protein At1g33090 hypothetical protein At1g33100 unknown protein At1g33110 unknown protein At1g47530 hypothetical protein At1g51340 hypothetical protein At1g58340 hypothetical protein At1g61890 hypothetical protein At1g64820 hypothetical protein At1g66760 hypothetical protein At1g66780 hypothetical protein At1g71140 hypothetical protein At1g71870 hypothetical protein At1g73700 putative integral membrane protein At2g04040 hypothetical protein At2g04050 hypothetical protein At2g04070 hypothetical protein At2g04080 hypothetical protein At2g04090 hypothetical protein At2g04100 hypothetical protein At2g21340 unknown protein At2g34360 hypothetical protein At2g38330 hypothetical protein		At2g38510 hypothetical protein predicted by grail At3g03620 unknown protein At3g08040 putative integral membrane protein At3g21690 integral membrane protein, putative At3g23550 unknown protein At3g23560 ALF5 aberrant lateral root formation 5 At3g26590 integral membrane protein, putative At3g59030 putative protein At4g00350 coded for by A. thaliana cDNA H76622 At4g21900 putative protein At4g21910 putative protein At4g22790 predicted protein At4g23030 putative protein At4g25640 putative protein At4g29140 putative protein At4g38380 putative protein At4g39030 EDS5 enhanced disease susceptibility protein 5 At5g10420 putative protein At5g17700 putative protein At5g19700 putative protein At5g38030 putative transmembrane protein At5g44050 putative protein At5g49130 putative protein At5g52050 integral membrane protein-like At5g52450 putative protein At5g65380 putative protein
	Yeast Families
	YHR032W ERC1 Ethionine resistance protein YDR338C YD38 probable membrane protein
	Rice Families (Coming Soon!)

A distributed project investigating gene networks that control uptake and accumulation of plant nutrients and toxic metals. Funded by the plant genome program of the National Science Foundation (DBI-0077378). Any opinions, findings, and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the National Science Foundation.

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